Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.
Effects
Melanotan is related to a hormone called "melanocyte-stimulating hormone" that exists in our bodies. The amount of skin-darkening pigments produced rises due to this hormone. Non-selectively imitating the effects of melanocortin peptides is melanotan II. These are organic hormones that affect the cardiovascular system, the immune system, inflammation, energy homeostasis, pigmentation, and sexual function. Similar to melanotan I (afamelanotide), melanotan II increases eumelanin synthesis, resulting in skin darkening (tanning). Melanotan encourages the body to produce more melanin, which results in a rich, natural tan. By raising the body's melanin content, the body is attempting to protect itself against excessive sun exposure. Your body's natural defense against UV damage is melanin. The skin eventually becomes darker as a result. Melanotan II is often given as a liquid injection beneath the skin, typically every other day. The tanning effect can start occurring after 5 dosages, according to studies.
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Melanotan may also induce penile erections by working on the brain. Male erections were discovered to be strongly stimulated by melanotan II during clinical trials for its usage as a tanning agent. Bremelanotide, a brand-new medication based on melanotan II, was created to benefit from this characteristic. It has been observed in numerous studies to boost male erection hardness and duration as well as male sexual desire. In patients with sexual arousal disorders, it has also been demonstrated to increase female sexual desire.
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The regulation of sexual function is also thought to be influenced by central melanocortin receptors, which stimulate lordosis in female rats and erectile activity in male rats as well as in humans. MC4R is linked to erectile function in both the central and peripheral nervous systems, while MC3R is linked to lordosis. Melanocortins have been investigated in clinical trials to treat both female and erectile dysfunction.
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Bremelanotide (PT-141), a different melanocortin MC4R-specific compound, appears to be the first "true" aphrodisiac after being administered to female rats in laboratory trials. Preliminary clinical findings also suggest a role in boosting sexual desire and arousal in women. Studies utilizing animal models have shown that pre-copulatory behaviors in female rats equivalent to sexual arousal are generated. Melanocortin peptides have been shown to modulate dopaminergic neurotransmission in studies, and this can have an impact on sexual behavior through reward-based neuropharmacology.
Doses
The dose of Melatonan 2 depends on your body weight,This is example for average 70kg adult 0.25mg-very light 0.5mg-light 1mg-common standard 1.5-strong 2mg-very strong .
Accourding to this ,100kg male can take 1.5-2mg as a weekly dose and 50kg female should start off with 0.25mg to be safe and then move to 0.5mg and 1mg if needed, pre-loading dose is 2x or 3x smaller than your normal maintenance dose. Reminder. you dont need to do this unless your are in rush to get really dark in a matter of days.
Melanotan is dose-dependant, that means more you use, darker your skin tone will be. But there's no need to overdo it.
Cycles
Up to 14 days. This cycle has not been repeated according to the available research. Accordingly, grant at least a few monthsā washout period or preferably administer the cycle only annually.

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