Raloxifene is a medicine used in the treatment and prevention of osteoporosis in postmenopausal women. It helps in preventing bone loss that can develop in women after menopause. It makes the bone stronger and lowers the risk of fractures.
Osteoporosis represents an increased risk for developing fractures. Raloxifene is a selective estrogen receptor modulator with an estrogen-agonistic effect on bone receptors.
Raloxifene can counteract the effects of high estrogen levels in men, which is why it has been explored as a treatment option.
Effects
A small minority of women experience:
- Uncomfortable hot flushes
- Leg cramps
- Swollen ankles
- Flu-like symptoms.
Less common side-effects include blood clots in the legs or inflammation in the leg veins, but this treatment won't be used if you have a history of these.
Doses
Raloxifene is taken in 60 mg tablets once a day.
It's important to continue treatment as your doctor advises ā even though you won't be able to feel whether it's working
Cycles
You take raloxifene once a day. You can choose the best time to take it but try to take it at about the same time every day.

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